Decibel Therapeutics Topline Results/Interim Analysis: Phase1b Study of DB-020 in Patients Treated with Cisplatin Chemotherapy

Laurence joined Decibel in January 2020. He previously served as an entrepreneur in residence at Third Rock Ventures, where he focused on novel drug discovery and development opportunities. Before that, Laurence was CEO of Warp Drive Bio, a small molecule company focused on novel oncology and antibiotic drug discovery based on natural products, until its merger with Revolution Medicines in 2018. Prior to that, he was the senior vice president and chief business officer of Alnylam Pharmaceuticals, where he was responsible for the company’s business development, finance and legal functions. Before coming to Alnylam, Laurence was the chief business officer at Ensemble Discovery, where he led the company’s strategic planning and corporate development efforts. Laurence previously spent ten years at Millennium Pharmaceuticals in a range of general management and business development positions. In addition to his professional interests, Laurence is a board member of the Possible Project, a board member of Garuda Therapeutics and board advisor to Life Science Cares. He earned his Ph.D. from King’s College London and his B.A. from Cambridge University.

John Lee joined Decibel in September 2016 as senior vice president of pharmaceutical development and brings over 20 years of experience in the biotechnology industry. Prior to Decibel, he served as senior vice president of pharmaceutical development at Infinity Pharmaceuticals. Throughout his 15 years at Infinity, John held roles of increasing responsibility and leadership. Most recently, he was responsible for chemistry manufacturing and control (CMC), analytical sciences, formulation sciences and clinical supply and distribution for the company’s drug candidates across all phases of global clinical development. He was also co-chair of Infinity’s operational leadership team. Previously, John was a new product manager at Corning Life Sciences, where he was responsible for developing new life science products. Before Corning, John was an early member of Millennium Pharmaceuticals and played a key role in the successful positional cloning of the mouse obesity gene tubby, before becoming project lead for an ovarian cancer diagnostic program. Prior to Millennium, John worked in the developmental chronobiology lab of Steven Reppert at Massachusetts General Hospital, where he focused on cloning G-protein coupled receptors and circadian biology. John received his bachelor’s degree in materials science and engineering from the Massachusetts Institute of Technology.

Jonathon Whitton is a clinician-scientist and vice president, clinical research at Decibel Therapeutics. Prior to joining Decibel in 2016, Jonathon conducted clinical research with people living with hearing loss at the Cincinnati Children’s Hospital Medical Center and Massachusetts Eye and Ear Infirmary. Jonathon is active in the American Academy of Audiology where he is a member of the Scientific Advisory and Research Council and chairs the annual translational research meeting in conjunction with the national conference. Jonathon received his Au.D. from the University of Louisville and his Ph.D. in Health Sciences and Technology from the Massachusetts Institute of Technology.